Robert Sindelar


About the Principal Investigator

E-mail: sindelar@interchange.ubc.ca
Phone: 604-822-2343

Training

Degree: M.S. Medicinal Chemistry and Natural Products
Institution: University of Iowa
Period: 1975
Degree: Ph.D, Medicinal Chemistry and Natural Products
Institution: University of Iowa
Period: 1980

Previous Positions

Position: Chair and Professor, Medicinal Chemistry
Institution: University of Mississippi, Research Institute for Pharmaceutical Sciences
Period: 2001 - 2002
Position: Interim Dean and Executive Director
Institution: School of Pharmacy, University of Mississippi
Period: 2000 - 2001
Position: Chair and Professor, Medicinal Chemistry
Institution: University of Mississippi, Research Institute for Pharmaceutical Sciences
Period: 1996 - 2000
Position: Research Institute for Pharmaceutical Sciences
Institution: Chair and Associate Professor University of Mississippi
Period: 1993-1996
Position: Preceptor
Institution: Associate Professor Research Institute for Pharmaceutical Sciences
Period: 1989 – 1996
Position: Assistant Professor
Institution: University of Mississippi
Period: 1985-1989

Current Position

Position: Present, Professor & Dean, Faculty of Pharmaceutical Sciences
Institution: University of British Columbia

Major Awards

Name: Received award for recognition of contributions to pharmacy in Mississippi
Organization: Mississippi Society of Health-Systems Pharmacists
Period: 2001
Name: Received Honorary Pharmacy License
Organization: Mississippi State Board of Pharmacy
Period: 2001
Name: Pharmacy Distinguished Alumnus Award
Organization: University of Iowa College
Period: 2005
Name: Loyd E. Harris Lecturer
Organization: University of Oklahoma College of Pharmacy
Period: 2005
Name: The Just Desserts Award
Organization: UBC Alma Mater Society
Period: 2006
Name: Friend of Pharmacy Award
Organization: B.C. Pharmacy Association
Period: 2006
Name: Elected to the Canadian Academy of Health Sciences
Period: 2008

Research Interests

  • Natural Products Isolation, design, synthesis and pharmacological evaluation of potential immunomodulators and agents to combat infectious diseases.
  • Rationally-designed enzyme inhibitors.
  • Computer-assisted molecular design and computational chemistry
  • Protein homology modeling
  • Topographical modeling of structurally-rigid natural products and their possible use in immune modulation, microbial chemotherapy, cardiovascular disease, and chemotherapy.

Selected Publications

  • Guo, Z, S Vangapandu, R W Sindelar, L A Walker and R D Sindelar. 'Biologically active quassinoids and their chemistry: potential leads for drug design'. Frontiers in Medicinal Chemistry. 4 (2009): in press.
  • Armstrong, PW, LJ Dempster, DG Hawkins, M law, TH Ogilvie, C Orchard, MT Schechter, RD Sindelar, CI Whiteside. 'The birth of the Canadian Academy of Health Sciences’. Clinical Investigation of Medicine. 28.2 (2005): 43 – 45.
  • Guo, Z, S Vangapandu, A Nimrod, LA Walker and R D Sindelar. 'Synthesis of A/B-ring partial analogs of bruceantin as potential antimalarial agents'. Medicinal Chemistry. 1.1 (2005): 3 – 11.
  • Guo, Z, S Vangapandu, R W Sindelar, L A Walker and R D Sindelar. 'Biologically active quassinoids and their chemistry: potential leads for drug design'. Current Medicinal Chemistry. 12.2 (2005): 173 - 190.
  • Bradbury, Barton J, Piotr Bartyzel, Teodoro S Kaufman, Marcelo J Nieto, Robert D Sindelar, Susanne M Scesney, Bruce R Gaumond and Henry C Marsh. 'Synthesis and complement inhibitory activity of B/C/D-ring analogues of the fungal metabolite 6,7-diformyl-3',4',4a',5',6',7',8',8a'-octahydro-4,6',7'-trihydroxy- 2',5',5',8a'-tetramethylspiro[1'(2'H)-naphthalene-2(3H)-benzofuran].'. Medicinal Chemistry. 46.13 (2003): 2697 - 2705.
  • Bradbury, BJ, P Bartyzel, T S Kaufman, M J Nieto, R D Sindelar, S M Scesney, BR Gaumond and H C Marsh. 'Synthesis and complement inhibitory activity of B/C/D-ring analogues of the fungal metabolite 6,7-diformyl-3',4',4a',5',6',7',8',8a'-octahydro-4,6',7'-trihydroxy- 2',5',5',8a'-tetramethylspiro[1'(2'H)-naphthalene-2(3H)-benzofuran]'. Medicinal Chemistry. 46.13 (2003): 2697 - 2705.
  • Muri, EM, MJ Nieto, R D Sindelar and J S Williamson. 'Hydroxamic acids as pharmacological agents'. Current Medicinal Chemistry. 9.17 (2002): 1631 - 1653.
  • Assefa, H, A Nimrod, L Walker and R Sindelar. 'Enantioselective synthesis and complement inhibitory assay of A/B-ring partial analogues of oleanolic acid.'. Bioorganic & Medicinal Chemistry letters. 11.13 (Jul 9, 2001): 1619 - 1623.

Books:

  • Crommelin, DJA, Meibohm, B and R D Sindelar, ed. Pharmaceutical biotechnology, An Introduction for Pharmacists and Pharmaceutical Scientists. 3rd. New York: Informa Healthcare Publishers, 2007.
  • Crommelin, DJA, Meibohm, B and R D Sindelar, ed. Pharmaceutical biotechnology, An Introduction for Pharmacists and Pharmaceutical Scientists. Textbook Edition. New York: Informa Healthcare Publishers, 2007.
  • Sindelar, R D. Chapter 7: Genomics, Proteomics, and Additional Biotechnology-Related Techniques'. Pharmaceutical Biotechnology, An Introduction for Pharmacists and Pharmaceutical Scientists. Ed. DJA Crommelin, B Meibohm and R D Sindelar. 3rd. New York: Informa Healthcare Publishers, 2007. 133 – 174.
  • Reid, RE and RD Sindelar. Chapter 6: Pharmaceutical Biotechnology – From Nucleic Acids to Personalized Medicine. Foye’s Principles of Medicinal Chemistry. Ed. TL Lemke, DA Williams, VF Roche, and SW Zito. 6th. Philidelphia: Wolters Kluwer|Lippincott Williams & Wilkins, 2007. 115 – 174. ( previously sole author of chapter entitled: 'Pharmaceutical Biotechnology' in 5th. 2001, and 4th. 1995 editions.
  • Crommelin, DJA and R D Sindelar, ed. Pharmaceutical biotechnology. 2nd. Philadelphia: Taylor & Francis, 2002.
  • Sindelar, R D. 'Chapter 6: Genomics, Proteomics, and Additional Biotechnology-Related Techniques'. Pharmaceutical Biotechnology, An Introduction for Pharmacists and Pharmaceutical Scientists. Ed. DJA Crommelin and R D Sindelar. 2nd. Philadelphia: Taylor & Francis, 2002. 133 - 172.
  • Evens, RP and R D Sindelar. 'Chapter 20: Biotech Products in the Pipeline'. Pharmaceutical Biotechnology, An Introduction for Pharmacists and Pharmaceutical Scientists. Ed. DJA Crommelin and R D Sindelar. 2nd. Philadelphia: Taylor & Francis, 2002. 389 - 406.

 

« Back



a place of mind, The University of British Columbia

Faculty of Pharmaceutical Sciences
2146 East Mall
Vancouver, BC, Canada V6T 1Z3
Tel (Dean’s Office): 604.822.2343

Emergency Procedures | Accessibility | Contact UBC | © Copyright The University of British Columbia