Padmesh Rajput


About the Students

Padmesh Rajput
E-mail: padmesh@interchange.ubc.ca
Phone: 604-827-3672

Training

Degree: M. Sc
Institution: University of Hertfordshire, UK
Period: 2006
Degree: B. Pharmacy
Institution: College of Pharmacy, IPS Academy, India
Period: 2003

Current Position

Position: Ph.D. Candidate
Supervisors: Dr. Ujendra Kumar

Scholarships + Awards

Name: Subhash C. Verma Memorial Prize in Pharmaceutical Sciences
Period: 2009
Name: John H. McNeill Scholarship
Period: 2008
Name: Young Neuroscientist Award (CAN-ACN and Eli Lilly)
Tenure period: 2007-2008
Name: Teaching Assistant Appreciation Award
Tenure period: 2007-2008
Name: Teaching Assistant Appreciation Award
Tenure period: 2006-2007
Name: PhD tuition Award
Tenure period: 2006-2009
Name: International Student Scholarship Award
Tenure period: 2005-2006

 

About The Research

To determine the role of Somatostatin and Somatostatin receptors in neurodegenerative diseases such as Alzheimer's and Huntington's disease

Publications + Presentations

Publications
  • Rajput PS, Kharmate G, Somvanshi RK, Kumar U. Colocalization of dopamine receptor subtypes with dopamine and cAMP-regulated phosphoprotein (DARPP-32) in rat brain. Neurosci Res. 2009 Sep; 65(1):53-63.
  • Rajput PS, Billova S, Patel SC, Kharmate G, Somvanshi RK, Kumar U. Expression of somatostatin and somatostatin receptor subtypes in Apolipoprotein D (ApoD) knockout mouse brain: An immunohistochemical analysis. JChem Neuroanat. 2009 Sep;38(1):20-3.
  • Somvanshi RK, Billova S, Kharmate G, Rajput PS, Kumar U. C-tail mediated modulation of somatostatin receptor type-4 homo- and heterodimerizations and signaling. Cell Signal. 2009 Sep; 21 (9):1396-414.
  • Nagareddy, P.R., Soliman, H., Lin, G., Rajput, P.S., Kumar, U., McNeill, J.H. and MacLeod, K.M. Selective Inhibition of Protein Kinase C β2 Attenuates Inducible Nitric Oxide Synthase Mediated Cardiovascular Abnormalities in Streptozotocin -Diabetic Rats. Diabetes; 2009 Oct;58(10):2355-64.
Conference abstracts & Poster presentations
  • Rajput P.S., Kharmate G, Somvanshi R. K., Liu S. H., Brunicardi F. C., Kumar U. Somatostatin receptor type 1 and 5 knock out mouse (SSTR1/5 KO) is associated with the activation of NMDA receptors and loss of DARPP-32 immunoreactivity in brain. Society for Neuroscience, Chicago. Oct 17-21, 2009
  • Marsiglia W., Rajput P.S., Kumar U., Thanos P. K., Effects of the adenosine A2A antagonists caffeine and RX821002 on the expression of dopamine D1-D5 receptors. Society for Neuroscience, Chicago. Oct 17-21, 2009.
  • Somvanshi R. K., Kharmate, G., Rajput, P.S., War S.A., Kumar, U. “Role of C-tail in homo-and heterodimerization of human somatostatin receptor type-4 (hSSTR4): implication in receptor internalization and cell signaling.” 91st Annual Meeting Endo 09: Washington, DC, June 10-13, 2009
  • Rajput P.S., Kharmate G., Khan Z., Somvanshi R. K., Marzban L., Kumar U. Role of Prohormone Convertase 2 on Expression of Carboxypeptidase E, Prohormone Convertase 1, Somatostatin and Somatostatin Receptors in PC2 Knockout Mice Brain. 3rd Canadian Neuroscience Conference, Vancouver, Canada. May, 2009.
  • Rajput P.S., Kharmate G., Khan Z., Somvanshi R. K., Marzban L., Kumar U. Role of Prohormone Convertase 2 on Expression of Carboxypeptidase E, Prohormone Convertase 1, in PC2 Knockout Mice Brain. 7th BC Genome Forum Vancouver, Canada. April, 2009.
  • Kharmate G, Rajput, P. S, Somvanshi R. K and Kumar U. 'Modulation of Epidermal Growth Factor Mediated Signaling Pathways by Somatostatin Receptors: Implication in the Pathophysiology of Breast Cancer'. UCIC World Cancer Congress. Geneva, Switzerland. Aug, 2008.
  • Leung L., Kharmate G., Qiu X., Rajput P.S., Billova S. and Kumar U.,Regulation of the membrane expression of somatostatin receptor subtypes (SSTR 1 to 5) under tamoxifen and estradiol treatment and the effect of oxidative stress on the cell-death pathway in human breast cancer cells. Canadian Society of Pharmaceutical Sciences Symposium, Banff, Alberta, 2008.
  • Rajput, P.S, Kharmate G, Somvanshi R. K and Kumar U. 'Receptor and Region Specific Colocalization and Functional Interaction of Dopamine Receptors 1-5 with DARPP-32 in Rat Brain and Cultured Striatal Neurons'. 2nd Canadian Neuroscience Conference. Montreal, Quebec, Canada. May, 2008.
  • Rajput, P.S, Kharmate G, Somvanshi R. K, Kumar U. 'Colocalization of Somatostatin Receptors 1-5 with DARPP-32 in Rat Brain and Cultured Striatal Neurons'. Society of Neuroscience. Washington D.C. Nov, 2008.
  • Kharmate G, Heather Watt, Rajput, P.S, Sabina Billova, Xiaofan Qui, Kumar U. Epidermal Growth factor receptors activated signaling pathways is modulated in the presence of Somatostatin receptors. Canadian Cancer Research Conference. Toronto, Ontario, Canada. Nov, 2007
  • Rajput, P.S, Kharmate G, Sabina Billova and Kumar U. 'Colocalization and Functional Interaction of Dopamine Receptors 1-5 with DARPP-32 in Rat Brain and Cultured Striatal Neurons'. Neuron on the Map. San Diego, California, Nov, 2007Neurons". 2nd Canadian Neuroscience Conference. Montreal, Quebec, Canada. May, 2008.
  • Billova, S., Rajput P.S., Patel S. and Kumar U. "Somatostatin receptor expression in the brain of apolipoprotein D knockout mice.” 36th Annual Meeting of Society for Neuroscience. Atlanta, Georgia, United States. Nov, 2006.
Other Poster Presentations
  • Khan, Z, Rajput P.S., Kharmate G. and Kumar U. "Expression Of Somatostatin (Sst), Somatostatin Receptors 1-5 Carboxypeptidase-E (Cpe), And Prohormone Convertase 1 (Pc1) In Prohormone Convertase 2 (Pc2) Knock-Out Mice Brain". SSRP 2008. Vancouver, Canada. Sept., 2008.
  • Leung L., Kharmate G., Qiu X., Rajput P. S., Billova S, and Kumar U. “The Expression of Somatostatin Receptor Subtypes (SSTR1-5) Under Tamoxifen and Estradiol Treatment and the Effect of Oxidative Stress on Human Breast Cancer Cells”. SSRP 2007. Vancouver, British Columbia, Canada. Sept., 2007.
  • Rajput P.S., Churchman A. and Hoffman R. “Effects of Resveratrol derivatives from peanuts on COX-2 induction in J774 Cells”. 3rd Annual Physiology & Pharmacology Research day, University of Hertfordshire, U.K. April, 2005.

 

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